Innovent Biologics Presents Phase 3 Data Showing Arcotatug Tavetecan Meets Survival Endpoints

By Public Technologies
  • Innovent Biologics’ arcotatug tavetecan met overall survival and progression-free survival endpoints in the Phase 3 G-HOPE-001 trial.
  • Median overall survival reached 10.2 months versus 6.9 months with physician’s-choice treatment.
  • Median progression-free survival was 7.1 months versus 3.1 months with physician’s-choice treatment.
  • China accepted the drug’s application, making it the first CLDN18.2 ADC under regulatory review globally; Japan filing is targeted for 2027.
  • IBI354 combined with pertuzumab achieved a 95% response rate in 20 patients with HER2-positive breast cancer; no interstitial lung disease occurred.


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