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Immutep's IMP761 Shows Significant Suppression of T-Cell Immune Responses in Phase I Trial

By Public Technologies
  • Immutep announced positive Phase I results for IMP761 in healthy volunteers, presented at ACR Convergence 2026.
  • A single infusion significantly suppressed T-cell-driven immune responses, with stronger effects at higher drug exposure.
  • IMP761 was well tolerated across all seven dose levels, with no serious or severe adverse events reported.
  • The ongoing multiple-dose phase has shown no new safety signals; the drug's pharmacokinetic profile supports dosing every four weeks.
  • Results from the multiple-dose phase are expected in the first half of 2027 to guide dose selection for a potential Phase II program.


Disclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Immutep Ltd. published the original content used to generate this news brief on November 09, 2026, and is solely responsible for the information contained therein.

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