Cytokinetics Publishes Presentation on Aficamten in Nonobstructive Hypertrophic Cardiomyopathy

By Public Technologies
  • Cytokinetics published “Effect of Aficamten on Cardiac Structure and Function in Nonobstructive Hypertrophic Cardiomyopathy: The ACACIA-HCM CMR Study.”
  • The presentation highlighted significantly greater improvements in exercise capacity and health status with aficamten versus placebo in the pivotal Phase 3 trial.
  • Peak oxygen uptake showed a least-squares mean difference of 0.67 mL/kg/min versus placebo (P=0.003).
  • The cardiac magnetic resonance substudy enrolled 69 patients; 61 (88.4%) completed baseline and week 36 scans.


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