Coherus Oncology Publishes Presentation on Tagmokitug Interim Clinical Data

By Public Technologies
  • Coherus Oncology published “Tagmokitug CCR8+ Treg Depleter Interim Clinical Update,” reporting interim results in esophageal cancer.
  • First-line tagmokitug with toripalimab and chemotherapy achieved a 75% confirmed response rate among eight evaluable patients.
  • Second-line treatment at 700 mg showed median progression-free survival of 5.5 months; data remain immature.
  • Grade 3 or higher adverse events related to tagmokitug affected 20% of first-line patients versus 23.5% in second-line treatment.
  • Plans include expanding first-line enrollment to 30–40 patients, with parallel first- and second-line development targeting global pivotal trials.


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