AbelZeta reports 91.7% disease control rate in Phase I liver cancer trial of C-CAR031

By Public Technologies
  • AbelZeta announced updated Phase I results for C-CAR031, now AZD7003, in advanced liver cancer, previously presented at ESMO on October 26, 2026.
  • The trial in 36 heavily pretreated patients showed tumor shrinkage, an encouraging survival signal and a manageable safety profile.
  • Serious inflammatory reactions and lung disease occurred at the highest dose, though no dose-limiting toxicities were observed.
  • AstraZeneca holds sole worldwide development, manufacturing and commercialization rights following its January 2026 acquisition of remaining China rights.
  • AbelZeta remains eligible for milestone payments and royalties under existing agreements.


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