Nasdaq top and bottom performing stocks at about 02:45 p.m. EDT on 2026-10-01

By Reuters News

Nasdaq 100 .NDX

Top Performers

Percent Change

Synopsys, Inc.

+12.9%

Lumentum Holdings Inc.

+7.1%

Cadence Design Systems, Inc.

+5.8%

Strategy Inc

+4.7%

Roper Technologies, Inc.

+3.7%

Bottom Performers

Percent Change

Alnylam Pharmaceuticals, Inc.

-5.2%

AppLovin Corporation

-2.7%

Vertex Pharmaceuticals Incorporated

-2.6%

MercadoLibre, Inc.

-2.4%

Amgen Inc

-2.3%

  • The Nasdaq 100 .NDX gained 133.88 points, or 0.44%, to 30,542.39 and recorded one new high and 3 new lows. 60 stocks rose and 40 fell as advancing issues outnumbered decliners by a about a 1.5-to-1 ratio.

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