Pfizer Inc. (PFE) is a U.S. multinational company with headquarters in New York. Established in 1849, the company deals with discovering, developing, producing and selling pharmaceuticals. The company manufactures a broad range of medicines and vaccines for such therapeutic areas as immunology and inflammation, cardiovascular and metabolic diseases, oncology, neurologic and psychiatric illnesses, rare diseases. Pfizer is involved in carrying out clinical trials and conducting research and development. Pfizer is listed on four stock exchanges: the New York Stock Exchange, the London Stock Exchange, Euronext and the SIX Swiss Exchange. The company is also a member of the Dow Jones Industrial Average.