Zymeworks' ZW191 shows 64.5% response rate at 6.4 mg/kg in Phase 1 ovarian cancer trial

By Public Technologies
  • Zymeworks presented Phase 1 results for ZW191 in platinum-resistant ovarian cancer at ESMO Congress 2026.
  • The treatment showed anti-tumor activity across folate receptor alpha expression levels in heavily pretreated patients, with durable responses.
  • The lower dose had a more favorable tolerability profile, supporting its consideration for further development.
  • Results will guide dose selection, with continued development envisioned through a partnership or strategic collaboration.


Disclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Zymeworks Inc. published the original content used to generate this news brief via GlobeNewswire (Ref. ID: 202610240230PRIMZONEFULLFEED9851687) on October 24, 2026, and is solely responsible for the information contained therein.

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