Medtronic presents trial design for Evolut TAVR in moderate aortic stenosis

By Public Technologies
  • Medtronic presented EXPAND TAVR II’s design and patient characteristics at TCT on October 31, 2026, ahead of future clinical results.
  • The trial tests whether earlier Evolut transcatheter valve replacement with guideline-directed medical therapy improves outcomes versus medical therapy alone in moderate aortic stenosis.
  • Enrollment totaled 692 patients at 96 sites across 16 countries, targeting adults aged 65 or older with additional risk features.
  • Safety will be assessed at 30 days and effectiveness at two years, with follow-up planned through 10 years.


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