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GenFleet's GFH276 Shows 41.1% Response Rate in Early-Stage Pancreatic Cancer Trial

By Public Technologies
  • GenFleet Therapeutics presented initial Phase Ia results for oral pan-RAS inhibitor GFH276 at the ESMO annual meeting on October 25, 2026.
  • The treatment showed preliminary antitumor activity in previously treated pancreatic and non-small cell lung cancers.
  • Safety findings were favorable, with generally manageable treatment-related side effects and no dose-limiting toxicities across the highlighted dose range.
  • The findings support advancing GFH276 into mid- to late-stage studies as a standalone treatment and in combination regimens.


Disclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Genfleet Therapeutics (Shanghai) Inc. published the original content used to generate this news brief via IIS, the regulatory disclosure system operated by the Hong Kong Stock Exchange (HKex) (Ref. ID: HKEX-EPS-20261026-12382433), on October 26, 2026, and is solely responsible for the information contained therein.

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