AstraZeneca's Tezspire improves eosinophilic esophagitis symptoms in Phase III trial
- AstraZeneca and Amgen’s Tezspire met the Phase III CROSSING trial’s main goals in eosinophilic esophagitis, improving swallowing symptoms and tissue inflammation versus placebo.
- Benefits persisted through one year; treatment also cleared visible signs of disease in some patients.
- Results were presented at United European Gastroenterology Week 2026 in Barcelona, Spain.
- The safety profile was consistent with existing indications.
- AstraZeneca plans to share the findings with regulators to pursue Tezspire’s use in eosinophilic esophagitis.
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