Amgen's Tezspire achieves sustained remission in Phase 3 eosinophilic esophagitis trial

By Public Technologies
  • Amgen and AstraZeneca announced positive Phase 3 CROSSING results for Tezspire in adolescents and adults with uncontrolled eosinophilic esophagitis.
  • Tezspire improved swallowing symptoms and tissue inflammation versus placebo, with benefits sustained through one year.
  • More treated patients achieved complete endoscopic remission, with no visible disease features.
  • The safety profile was consistent with existing indications; eosinophilic esophagitis remains an investigational use.
  • Results will be presented at United European Gastroenterology Week 2026 in Barcelona.


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