Medtronic's Symplicity device lowers blood pressure in six-month real-world study
- Medtronic reported significant blood pressure reductions at six months in its SPYRAL AFFIRM study of the Symplicity Spyral renal denervation system.
- Improvements occurred without increased blood pressure medication use, with similar reductions across diverse patient groups.
- Results were presented at TCT 2026 and simultaneously published in Circulation Cardiovascular Interventions.
- The FDA also cleared a U.S. labeling update incorporating additional clinical evidence for patients with hypertension and other conditions.
- The update covers isolated systolic hypertension, chronic kidney disease and type 2 diabetes; the indication for use remains unchanged.
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