Cullinan Therapeutics Reports Anti-Leukemic Activity in Phase 1 CLN-049 Study

By Public Technologies
  • Cullinan Therapeutics will present CLN-049 and velinotamig research at the ASH annual meeting in New Orleans, December 12-15, 2026.
  • A Phase 1 abstract reports CLN-049 anti-leukemic activity with a favorable safety profile in relapsed or refractory leukemia or myelodysplastic syndrome.
  • Updated results for CLN-049 regimens selected for Phase 2 will be presented December 13.
  • Trial-in-progress posters cover CLN-049 combination treatment for newly diagnosed acute myeloid leukemia and velinotamig for autoimmune cytopenias.
  • Preclinical findings to be presented show velinotamig selectively targets BCMA-expressing B-lineage cells driving autoimmune cytopenias.


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