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Aadi Bioscience (AADI) surges 12% on first-ever approval

By Robert Davis

21:11, 23 November 2021

Scientist using a pipette at a biomedical laboratory
. Photo: Shutterstock

Aadi Bioscience (AADI) stock surged 12% during pre-market hours on Tuesday to $32.20 after the US Food and Drug Administration (FDA) approved a drug that treats a rare form of cancer.

By the closing bell Tuesday, Aadi’s stock had sank to $24.32 per share, representing a 4.7% drop from its close price of $25.52 on Monday.

Fyarro was developed by Aadi to treat unresectable or metastatic malignant perivascular epithelioid cell tumor (PEComa). It is the first and only FDA-approved treatment for this cancer.

Dr. Neil Desai, founder and CEO of Aadi, called the approval a “momentous event” both for the patients who need the treatment and their caretakers.

Standard of care

Other doctors described Fyarro’s approval as a new weapon for treating patients who received a poor prognosis and have limited treatment options.

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Andrew Wagner, a senior oncologist at the Dana-Farber Cancer Institute in Boston, Massachusetts, said in a statement that the drug will be “welcomed by the physician community” because of its effectiveness at treating advanced forms of the cancer.

According to Fyarro’s Phase 2 results, the drug generated an overall response rate of 39% in patients with advanced PEComa.

Of the responders, more than 92% went into remission for at least six months. Two-thirds were in remission for at least one year, and 58% were in remission for two years.

Brendan Delaney, chief operating officer of Aadi, said the results could make Fyarro the “standard of care” for this cancer.

Read more: AstraZeneca buys rare disease drugmaker Caelum in 0m deal

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The main difference between CFD trading and trading assets, such as commodities and stocks, is that you don’t own the underlying asset when you trade on a CFD.
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