Switzerland's CRISPR Therapeutics Q3 CASGEVY revenue jumps 30% sequentially

By Reuters News


Overview

  • Switzerland-based gene-editing firm's Q3 CASGEVY revenue rose 30% sequentially, nearly six times yr/yr

  • Company expanded CASGEVY approvals for younger children in U.K. and Middle East

  • Q3 net loss widened to $111.4 mln from $106.4 mln a year ago


Outlook

  • Company expects updates from CTX611 Phase 2 trial in H2 2026

  • Phase 1b data for CTX310 in severe hypertriglyceridemia to be presented November 2026

  • Phase 1 data for zugo-cel in systemic sclerosis to be presented November 2026


Result Drivers

  • CASGEVY EXPANSION - Co said Q3 revenue growth was driven by expanded approvals and increased patient access for CASGEVY, including younger children in U.K. and Middle East

  • PATIENT INITIATION - Co said more than 750 patients have initiated CASGEVY treatment worldwide, with twice as many in first nine months of 2026 as in all of 2025

  • R&D SPEND - Co said increase in Q3 R&D expense was primarily due to higher external research and development expenses and sublicense fees


Company press release:


Key Details

Metric

Beat/Miss

Actual

Consensus Estimate

Q3 Loss Per Share

$1.15

Q3 Operating Expenses

$142.71 mln

Q3 Pretax Loss

$111.36 mln


Analyst Coverage

  • The current average analyst rating on the shares is "buy" and the breakdown of recommendations is 12 "strong buy" or "buy", 11 "hold" and no "sell" or "strong sell"


Reuters Recommended Reads

  • Nov 2 - FDA to review uniQure's Huntington's gene therapy, decision due on May 2027

  • Nov 2 - Tiziana's experimental MS treatment meets main goals in mid-stage study

  • Nov 2 - Axsome Therapeutics Q3 revenue rises on Auvelity and Sunosi


For questions concerning the data in this report, contact Estimates.Support@lseg.com. For any other questions or feedback, contact reuters.support@thomsonreuters.com.


(This story was created using Reuters automation and AI based on LSEG and company data. It was checked and edited by a Reuters journalist prior to publication.)

Capital.com is an execution-only brokerage platform and the content provided on the Capital.com website is intended for informational purposes only and should not be regarded as an offer to sell or a solicitation of an offer to buy the products or securities to which it applies. No representation or warranty is given as to the accuracy or completeness of the information provided.

The information provided does not constitute investment advice nor take into account the individual financial circumstances or objectives of any investor. Any information that may be provided relating to past performance is not a reliable indicator of future results or performance.

To the extent permitted by law, in no event shall Capital.com (or any affiliate or employee) have any liability for any loss arising from the use of the information provided. Any person acting on the information does so entirely at their own risk.

Any information which could be construed as “investment research” has not been prepared in accordance with legal requirements designed to promote the independence of investment research and as such is considered to be a marketing communication.