Madrigal's Rezdiffra improves or stabilizes liver stiffness in up to 93% of patients in real-world studies
- Madrigal Pharmaceuticals announced real-world Rezdiffra results presented at AASLD’s 2026 Liver Meeting for metabolic dysfunction-associated steatohepatitis.
- Most patients showed improved or stable liver stiffness roughly one year into treatment, with additional improvements in liver fat and cardiometabolic markers.
- Benefits were observed regardless of concurrent GLP-1 therapy, supporting use across patients with common metabolic conditions.
- Most patients remained on treatment at one year, with high adherence among those continuing therapy.
- Safety findings were consistent with clinical trials; reported treatment-related adverse events were infrequent.
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