Innovent's Sintbilo Meets Primary Endpoint in Phase 3 Cholesterol Trial
- Innovent Biologics today reported its Phase 3 CREDIT-5 trial of Sintbilo (tafolecimab) monotherapy met its primary endpoint.
- The 198-participant Chinese study showed significant cholesterol reductions versus placebo over 12 weeks in patients with non-familial hypercholesterolemia and mixed hyperlipidemia.
- Treatment showed favorable safety and tolerability, with no severe or serious treatment-emergent adverse events or new safety signals.
- The company plans to seek a new indication in China, potentially expanding Sintbilo’s use as a first-line standalone treatment for hyperlipidemia.
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