Immutep Publishes Presentation on IMP761 Phase I Study

By Public Technologies
  • Immutep published a medical research presentation on its LAG-3 agonist antibody IMP761, including interim Phase 1 results.
  • The placebo-controlled study in 60 healthy volunteers showed significant, exposure-dependent suppression of KLH-induced immune responses.
  • IMP761 was well tolerated across all tested doses, with no severe or serious adverse events reported.
  • Pharmacokinetic findings support dosing every four weeks at higher dose levels of 2.5-14 mg/kg.
  • Preclinical testing showed significantly reduced T-cell proliferation and activation in samples from rheumatoid arthritis patients.


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