U.S. STOCKS ON THE MOVEx-Microsoft, Nike, Nektar Therapeutics

September 25 (Reuters) - Wall Street's main indexes inched higher in choppy trading on Friday as AI optimism buoyed sentiment and oil prices eased, while investors monitored efforts to secure a deal to end the Middle East conflict. .N

At 11:31 EDT, the Dow Jones Industrial Average .DJI was up 0.40% at 51,557.78. The S&P 500 .SPX was up 0.23% at 7,722.19 and the Nasdaq Composite .IXIC was up 0.27% at 27,012.30.

The top three S&P 500 .PG.INX percentage gainers:

** Humana Inc. HUM.N, up 8.0%

** Bloom Energy Corporation BE.N, up 6.9%

** Akamai Technologies Inc , up 6.6%

The top three S&P 500 .PL.INX percentage losers:

** CBOE Global Markets, Inc. CBOE.Z, down 4.2%

** Gen Digital Inc. , down 3.6%

** Meta Platforms, Inc. , down 3.5%

The top three NYSE .PG.N percentage gainers:

** Surf Air Mobility Inc. SRFM.N, up 21.5%

** Atlas Energy Solutions Inc. AESI.N, up 17.0%

** Scully Royalty Ltd SRL.N, up 12.6%

The top three NYSE .PL.N percentage losers:

** ESS Tech, Inc. GWH.N, down 39.5%

** Sos Ltd SOS.N, down 8.3%

** Securitize Corp SECZ.N, down 7.2%

The top three Nasdaq .PG.O percentage gainers:

** Masonglory Ltd , up 202.0%

** INLIF Ltd , up 65.1%

** Wheeler Real Estate Investment Trust Inc , up 39.8%

The top three Nasdaq .PL.O percentage losers:

** Solowin Holdings Ltd , down 86.3%

** TruGolf Holdings Inc , down 35.1%

** CDT Equity Inc , down 32.5%

** Akamai Technologies Inc AKAM.O:
BUZZ - Surges on $11.6 billion Anthropic deal

** Comcast Corp CMCSA.O:
BUZZ - Falls; KeyBanc downgrades on broadband, theme park concerns

** Twilio Inc TWLO.N:
BUZZ - Slips after HSBC cuts to 'reduce' on AI monetization doubts

** 3M Co MMM.N:
BUZZ - Bernstein upgrades 3M, cites stronger growth and valuation outlook

** Costco Wholesale Corp COST.O:
BUZZ - Shares dip, brokerages cut PT after quarterly results

** Almonty Industries Inc ALM.O:
BUZZ - Gains after Stifel initiates coverage with 'buy'

** Delek US Holdings Inc DK.N:
BUZZ - Steadies after $400 mln convertible bond sale

** Nektar Therapeutics NKTR.O:
BUZZ - Gains; jury finds Lilly breached contract in drug partnership dispute

** CoreCivic Inc CXW.N:
BUZZ - Falls after CEO resigns

** Nike Inc NKE.N:
BUZZ - Down as BofA turns bearish, says 'risks are rising'

** IMAX Corp IMAX.N:
BUZZ - Morgan Stanley initiates IMAX with 'overweight' on premium entertainment demand

** Microsoft Corp MSFT.O:
BUZZ - Gains; co revamps Copilot with code generation, agentic AI tools

** Cardinal Infrastructure Group Inc CDNL.O:
BUZZ - Truist initiates on Cardinal Infra with 'buy'; shares rise

** ADARx Pharmaceuticals Inc ADRX.O:
BUZZ - Set to open higher in Nasdaq debut after upsized $446.3 million IPO