CFDs are complex instruments and come with a high risk of losing money rapidly due to leverage. Between 75-95% of retail investor accounts lose money when trading CFDs with this provider. You should consider whether you understand how CFDs work and whether you can afford to take the high risk of losing your money.
Open platformOpen platform

Spyre Therapeutics Q3 net loss widens to $96.12 million

By Public Technologies
  • Spyre Therapeutics’ third-quarter 2026 net loss widened year over year to $96.12 million.
  • Research and development expenses rose 97% to $89.17 million, driven by higher manufacturing costs and clinical trial expenses.
  • Cash, cash equivalents and marketable securities totaled $1.07 billion at September 30; expected funding runway extends into the second half of 2029.
  • SKYLINE combination-trial enrollment exceeded expectations, enabling a higher enrollment target; topline induction results remain expected in the third quarter of 2027.
  • SPY072 will not advance in rheumatic diseases following insufficient benefit in rheumatoid arthritis and missed primary endpoints in two other sub-studies.


Disclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Spyre Therapeutics Inc. published the original content used to generate this news brief via GlobeNewswire (Ref. ID: 202611031601PRIMZONEFULLFEED9869141) on November 03, 2026, and is solely responsible for the information contained therein.

Capital.com is an execution-only brokerage platform and the content provided on the Capital.com website is intended for informational purposes only and should not be regarded as an offer to sell or a solicitation of an offer to buy the products or securities to which it applies. No representation or warranty is given as to the accuracy or completeness of the information provided.

The information provided does not constitute investment advice nor take into account the individual financial circumstances or objectives of any investor. Any information that may be provided relating to past performance is not a reliable indicator of future results or performance.

To the extent permitted by law, in no event shall Capital.com (or any affiliate or employee) have any liability for any loss arising from the use of the information provided. Any person acting on the information does so entirely at their own risk.

Any information which could be construed as “investment research” has not been prepared in accordance with legal requirements designed to promote the independence of investment research and as such is considered to be a marketing communication.