Cabaletta Bio presents rese-cel data showing sustained one-year responses in all six adult dermatomyositis patients

By Public Technologies
  • Cabaletta Bio expects registrational RESET-Myositis topline results in the second half of 2027, targeting a myositis biologics license application in first-quarter 2028.
  • All six adult dermatomyositis patients maintained immunomodulator-free moderate-to-major responses through one year; 67% were steroid-free.
  • Safety data from 71 patients showed 94% had no cytokine release syndrome or grade 1 events; 96% had no neurotoxicity syndrome.
  • A development strategy for the preconditioning-free approach is expected in the first half of 2027.
  • Operational runway extends into first-quarter 2028, covering all anticipated milestones.


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