Argenx's Efgartigimod Meets Primary Endpoint in Phase 3 Autoimmune Myositis Trial
- argenx reported its Phase 3 ALKIVIA trial of efgartigimod met primary and key secondary endpoints in the combined autoimmune myositis population.
- Immune-mediated necrotizing myopathy (IMNM) patients showed significant, sustained improvement versus placebo, supporting a potential first treatment for the condition.
- A US filing for IMNM is planned by the end of 2026, supported by FDA Breakthrough Therapy Designation.
- Dermatomyositis patients showed clinically meaningful improvement, but results did not reach statistical significance in this smaller group.
- Results will be presented at ACR Convergence on November 11, 2026, from 9:15-9:30 a.m. ET.
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