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Chinook Therapeutics, Inc. Company profile

About Chinook Therapeutics Inc

Chinook Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on discovering, developing, and commercializing precision medicines for kidney diseases. The Company's development programs consist of Atrasentan, BION-1301 and CHK-336. Atrasentan is a potent and selective endothelin A receptor antagonist that are developed for the treatment of proteinuric glomerular diseases. BION-1301 is an investigational humanized IgG4 monoclonal antibody that blocks APRIL binding to both the B-cell maturation antigen (BCMA), and transmembrane activator and CAML interactor (TACI), receptors, as a disease-modifying therapy for Immunoglobulin A Nephropathy (IgAN). CHK-336 is a liver-targeted oral small molecule lactate dehydrogenase (LDHA), inhibitor, which are developed for the treatment of primary hyperoxaluria.

Financial summary

BRIEF: For the fiscal year ended 31 December 2021, Chinook Therapeutics Inc revenues increased from $827K to $51.6M. Net loss increased 26% to $102.9M. Revenues reflect an increase in demand for the Company's products and services due to favorable market conditions. Higher net loss reflects Research and Development-other increase from $24.8M to $66.1M (expense), Change in fair value of contingent consi increase from $1.5M to $27.3M (expense).